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Table 5 Centers for Disease Control and Prevention reference standards tested for anti-Rib-P antibodies

From: Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies

Sample Specificity ELISA, RUa Interpretation ALBIA, LUb Interpretation LIA Interpretation
CDC1 Anti-dsDNA 1.0 Borderline 143 Negative 0 Negative
CDC2 Anti-SS-B/La 0.3 Negative 97 Negative 0 Negative
CDC3 Speckled ANA 0.4 Negative 80 Negative 0 Negative
CDC4 U1-RNP 0.6 Negative 157 Negative 0 Negative
CDC5 Sm 0.6 Negative 89 Negative 0 Negative
CDC6 Nucleolar; anti-fibrillarin 0.3 Negative 210 Negative 0 Negative
CDC7 SS-A/Ro60 0.8 Negative 149 Negative 0 Negative
CDC8 Centromere 0.5 Negative 119 Negative 0 Negative
CDC9 Topoisomerase-I 0.9 Negative 166 Negative 0 Negative
CDC10 Jo-1 0.3 Negative 75 Negative 0 Negative
CDC11 PM/Scl 0.5 Negative 126 Negative 0 Negative
CDC12 Rib-P 6.6 Positive 11,664 Positive 3 Positive
  1. aCutoff = 1.5 relative units (RU); bcutoff = 350 luminescence units (LU). ALBIA, addressable laser bead immunoassay; CDC, Centers for Disease Control and Prevention; dsDNA, double-stranded DNA; ELISA, enzyme-linked immunosorbent assay; LIA, line immunoassay; Rib-P, ribosomal P protein.
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