Figure 3
Macroscopic pathology of joint swelling in rabbits with antigen-induced arthritis. (a) Photograph taken before arthritis onset. (b) Photograph taken 24 hours after arthritis onset. (c) The left knee of the rabbit with antigen-induced arthritis (AIA) was treated with daily intra-articular injections of 1 ng adrenomedullin (AM) for 7 days and the right knee was treated with daily intra-articular injections of saline for 7 days. Photograph taken 8 days after arthritis onset. (d) The left knee of the rabbit with AIA was treated with daily intra-articular injections of 3 μg AM for 7 days and the right knee was treated with daily intra-articular injections of saline for 7 days. Photograph taken 8 days after arthritis onset.