Skip to main content
Figure 1 | Arthritis Research & Therapy

Figure 1

From: T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis

Figure 1

Effects of therapeutic treatment with T-614 on disease progression in rats with established CIA. Rats were orally treated daily with T-614 at 5 mg/kg per day or 20 mg/kg per day; MTX at 1 mg/kg every 3 days; nimesulide at 10 mg/kg per day; T-614 at 10 mg/kg per day and MTX at 1 mg/kg every 3 days; or vehicle. Treatment began on day 12 after immunization with type II collagen until day 36. Data are expressed as mean ± standard error of the mean (n = 5 to 7). *P < 0.05, **P < 0.01, versus day 12 or the vehicle-treated rats. CIA, collagen-induced arthritis; MTX, methotrexate.

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us