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Table 1 Quantification of lymphocytic foci in the salivary and lacrimal glands of mice from several representative C57BL/6.NOD-Aec1Aec2R(n) recombinant inbred lines

From: Identification of possible candidate genes regulating Sjögren's syndrome-associated autoimmunity: a potential role for TNFSF4in autoimmune exocrinopathy

RI line

Age, weeks

Submandibular glands

Lacrimal glands

  

Number of mice

Positive

Average number of LF

Number of mice

Positive

Average number of LF

  

Male

Female

Number

Male and female

 

Male

Female

Number

Male and female

 

RI 34

20 and 24

6

7

3

23%

1.0 ± 0.0

6

7

7

54%

1.7 ± 0.4

RI 02

20 and 24

4

7

0

0%

0.0 ± 0.0

6

8

4

29%

1.5 ± 0.3

RI 06

20

4

ND

3

74%

4.0 ± 1.7

4

ND

4

100%

5.8 ± 4.1

RI 09

21 and 22

7

7

11

79%

3.0 ± 0.6

7

7

6

43%

2.8 ± 0.7

RI 12

24

7

4

5

45%

2.4 ± 0.7

7

4

10

91%

2.8 ± 0.6

RI 33

20 and 21

9

7

10

63%

2.2 ± 1.0

9

7

13

81%

6.5 ± 4.5

  1. LF, lymphocytic foci; ND, not done; RI, recombinant inbred.