Figure 4From: Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repairHypoxia-inducible factor (HIF)-2α-mediated induction of cartilage matrix synthesis by human articular chondrocytes (HACs) may be possible through the inhibition of specific HIF-2α targeting prolyl hydroxylase domain (PHD) enzymes.Back to article page