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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Interactions among type I and type II interferon, tumor necrosis factor, and β-estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus

Figure 4

Effect of cytokines or β-estradiol on the expressions of interferon-inducible genes. Peripheral blood mononuclear cells from three healthy donors were cultured with the indicated cytokines for 24 hours. RNA was analyzed by quantitative RT-PCR as described in Materials and methods. Relative expression of the indicated genes – interferon-induced protein with tetratricopeptide repeats 1 (IFIT1), interferon-induced protein with tetratricopeptide repeats 3 (IFIT3), and interferon alpha-inducible protein 27 (IFI27) – compared with their nonstimulated cultures is shown. Each bar represents the mean value of duplicate wells as compared with the nonstimulated control. Downregulated genes were arbitrarily assigned a negative value.

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Arthritis Research & Therapy

ISSN: 1478-6362

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