Table 2 Results of the transmission disequilibrium test in 100 French Caucasian families with rheumatoid arthritis
Gene | SNP reference (position and amino acid change) | Allele | Transmitted/untransmitted | P value |
|---|---|---|---|---|
TLR1 | rs5743618 (+7765 S602I) | G/T | 41/35 | 0.49 |
rs5743594 (+3663) | C/T | 21/24 | 0.65 | |
TLR2 | rs3804099 (+15591 N199N) | C/T | 52/46 | 0.54 |
rs4696480 (-1938) | T/A | 49/52 | 0.76 | |
TLR4 | rs2737191 (-3869) | A/G | 45/44 | 0;92 |
rs4986790 (+8719 D259G) | A/G | 10/12 | 0.67 | |
rs1554973 (+14229) | T/C | 33/34 | 0.9 | |
TLR6 | rs5743810 (+744 S249P) | C/T | 58/54 | 0.71 |
TLR9 | rs187084 (+3483 P545P) | C/T | 43/42 | 0.91 |
rs352140 (851) | T/C | 40/42 | 0.83 |