Table 3 Results of the genotype relative risk test in 100 French Caucasian families with rheumatoid arthritis
Gene | SNP reference | Genotype | Patients (n = 100) | Controls (n = 100) | P value |
|---|---|---|---|---|---|
TLR1 | rs5743618 (+7765 S602I) | GG | 52 | 49 | 0.67 |
GT | 44 | 44 | |||
TT | 4 | 7 | |||
rs5743594 (+3663) | CC | 71 | 71 | 0.41 | |
CT | 25 | 28 | |||
TT | 4 | 1 | |||
TLR2 | rs3804099 (+15591 N199N) | CC | 29 | 24 | 0.77 |
CT | 51 | 55 | |||
TT | 20 | 21 | |||
rs4696480 (-1938) | TT | 18 | 21 | 0.89 | |
TA | 56 | 53 | |||
AA | 26 | 26 | |||
TLR4 | rs2737191 (-3869) | AA | 46 | 47 | 0.29 |
AG | 44 | 41 | |||
GG | 10 | 12 | |||
rs4986790 (+8719 D259G) | AA | 89 | 90 | 1 | |
AG | 10 | 10 | |||
GG | 1 | 0 | |||
rs1554973 (+14229) | TT | 56 | 58 | 0.88 | |
TC | 39 | 36 | |||
CC | 4 | 5 | |||
TLR6 | rs5743810 (+744 S249P) | CC | 22 | 20 | 0.91 |
CT | 55 | 55 | |||
TT | 23 | 25 | |||
TLR9 | rs187084 (+ 3483 P545P) | CC | 18 | 16 | 0.89 |
CT | 45 | 48 | |||
TT | 36 | 35 | |||
rs352140 (-851) | TT | 34 | 24 | 0.36 | |
TC | 37 | 47 | |||
CC | 28 | 28 |