Figure 1

Expression of Fc receptors in healthy control individuals versus systemic lupus erythematosus patients. (a) Representative scattergrams of surface expression of FcγRI/CD64, FcγRII/CD32 and FcγRIII/CD16 on CD14⁺ monocytes from a healthy control individual (top) and a patient with systemic lupus erythematosus (SLE) (bottom). CD14⁺ monocytes were gated based on their forward/sideward scatter. (b- d) Expression of FcγRI/CD64, FcγRII/CD32 and FcγRIII/CD16, respectively (mean fluorescence intensity (MFI)) on SLE versus control monocytes. SLE patients with and without lupus nephritis (LN) are analyzed separately. Differences between groups were compared by Student's t test. (e) Comparison of FcγRI/CD64 expression (MFI) on monocytes from SLE patients without LN or with biopsy-proven World Health Organization class II, class III/IV, or class V LN. *P < 0.05 compared with SLE patients without LN (Student's t test).