Figure 2

FcγRI/CD64 expression on monocytes correlates with renal disease, C-reactive protein, and complement C3 levels. (a) FcγRI/CD64 expression levels on circulating monocytes from systemic lupus erythematosus (SLE) patients (both lupus nephritis (LN) and non-LN patients) correlated with increased serum creatinine (left) and blood urea nitrogen (BUN) (middle), as well as with proteinuria (microalbumin/creatinine ratio) (right). MFI, mean fluorescence intensity. Expression of FcγRI/CD64 correlated (b) positively with serum high-sensitivity C-reactive protein (HsCRP) levels and (c) negatively with serum C3 levels (Spearman's correlation). (d) Comparison of FcγRI/CD64 expression in SLE patients positive or negative for anti-dsDNA autoantibodies (Student's t test).