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Table 2 Differences in disease activity measures between females and males in the QUEST-RA Study according to the number of swollen joints

From: Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study

Number of swollen joints

Mean (standard deviation)

 

DAS28

TJC28

ESR

MD global

Pain

Patient global

Fatigue

HAQ

0–1

        

   Female

3.2 (1.2)

3.2 (5.3)

24 (19)

1.6 (1.8)

3.3 (2.6)

3.3 (2.5)

3.9 (2.9)

0.83 (0.75)

   Male

2.7 (1.2)

2.0 (3.9)

20 (21)

1.2 (1.5)

2.6 (2.5)

2.9 (2.6)

2.9 (2.7)

0.52 (0.62)

   P value

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

2–3

        

   Female

4.2 (1.1)

5.2 (5.4)

29 (22)

2.8 (1.9)

4.1 (2.6)

4.1 (2.4)

4.5 (2.8)

1.1 (0.71)

   Male

3.8 (1.2)

4.7 (5.7)

25 (26)

2.4 (1.8)

3.6 (2.4)

3.6 (2.3)

3.7 (2.6)

0.74 (0.62)

   P value

<0.001

0.26

0.11

0.013

0.010

0.010

0.001

<0.001

4–6

        

   Female

4.8 (1.1)

7.3 (6.0)

31 (23)

3.5 (2.0)

4.7 (2.5)

4.6 (2.4)

5.0 (2.7)

1.2 (0.71)

   Male

4.6 (1.3)

6.8 (6.2)

32 (27)

3.4 (2.0)

4.1 (2.5)

4.4 (2.4)

4.2 (2.7)

0.91 (0.64)

   P value

0.071

0.28

0.63

0.041

0.017

0.29

<0.001

<0.001

≥ 7

        

   Female

6.0 (1.2)

13 (8.0)

38 (25)

5.1 (2.1)

5.6 (2.5)

5.2 (2.5)

5.6 (2.6)

1.4 (0.75)

   Male

5.8 (1.3)

12 (7.8)

38 (28)

4.9 (2.1)

5.2 (2.3)

4.9 (2.4)

5.0 (2.6)

1.2 (0.68)

   P value

0.016

0.064

0.99

0.21

0.024

0.082

<0.001

<0.001

  1. P values are from Student t test for independent samples. DAS28, disease activity score using 28 joint counts; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; MD global, doctor global assessment; QUEST-RA, Quantitative Standard Monitoring of Rheumatoid Arthritis; TJC28, tender joint count-28.