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Figure 3 | Arthritis Research & Therapy

Figure 3

From: The response to oestrogen deprivation of the cartilage collagen degradation marker, CTX-II, is unique compared with other markers of collagen turnover

Figure 3

Measurement of type II collagen markers Helix-II, CTX-II, and PIIANP in ovariectomised rats. The percentage difference from baseline value (time (t) = 0) is shown for each rat treated with sham (white boxes), OVX+oestradiol (grey boxes), OVX+placebo (black boxes). (a) Serum levels of Helix-II; (b) urinary levels of CTX-II; (c) serum levels of PIIANP. Bars represent median values. The mean (standard deviation) baseline levels of Helix-II, CTX-II and PIIANP were 8.69 (6.48) ng/ml, 1675 (636.4) μg/mmol creatinine and 324.0 (141.4) ng/ml, respectively. The 95% range is indicated by the bars. Changes induced as a function of time were compared with each other and treatments were compared by one-way analysis of variance, where *p < 0.05 and ** p < 0.01.

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Arthritis Research & Therapy

ISSN: 1478-6362

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