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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice

Figure 4

Effects of pilocarpine infusion on glandular blood flow and salivary flow rate. (a) Parallel individual glandular blood flow measurements, (b) mean increase in glandular blood and (c) salivary flow after pilocarpine infusion (0.1 mg/100 g body weight) in BALB/c and nonobese diabetic (NOD) mice (Jackson Laboratories, Group 2). (a) Glandular blood flow is measured in perfusion units (PU) before (filled symbols) and after (open symbols) pilocarpine infusion. (b, c) Also shown are mean ± standard error of the mean values for each group. BALB/c mice (n = 7, black columns) and NOD mice (n = 7, grey columns). *P < 0.05, **P < 0.005 when comparing the same experimental conditions in BALB/c mice and NOD mice.

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