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Table 2 Absolute numbers of mice positive for chemokines

From: Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice

  CXCL13 CCL19
Treatment LT MO NT LT MO NT
Age in weeks     Acini/duct Infiltrate Acini/duct Infiltrate Acini/duct Infiltrate
9 - - 0/4 - - - - 4/4 0/4
12 2/4 1/4 4/4 4/4 0/4 4/4 1/4 4/4 2/4
16 4/4 4/4 4/4 4/4 0/4 4/4 4/4 4/4 3/4
19 2/4 4/4 3/3 3/4 0/4 2/4 2/4 2/3 1/3
  1. Treatment with either lymphotoxin-beta receptor-immunoglobulin fusion protein (LTβR-Ig) or mouse monoclonal IgG1 (MOPC 21) was started at week 9. Euthanization was carried out 1 week after the last injection. Mice receiving either LTβR-Ig or MOPC 21 and euthanized at 12 weeks of age had received 3 injections, those euthanized at 16 weeks of age had received 7 injections, and those euthanized at 19 weeks of age had received 10 injections. -, no mice in these groups; LT, mice treated with lymphotoxin-beta receptor-immunoglobulin fusion protein; MO, mice treated with mouse monoclonal IgG1; NT, mice not treated.