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Table 1 Juvenile idiopathic arthritis classification scheme

From: Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis



Systemic onset

Arthritis in one or more joints, 2 weeks of fever, plus ≥1 of: rash, hepatosplenomegaly, lymphadenopathy


Arthritis affecting one to four joints for first 6 months of disease: persistent, affects ≤4 joints throughout disease course; extended, affects >4 joints after the first 6 months

Polyarthritis, rheumatoid factor-negative

Arthritis affecting five or more joints in the first 6 months, negative rheumatoid factor

Polyarthritis, rheumatoid factor-positive

Arthritis affecting five or more joints in the first 6 months, positive rheumatoid factor (on two separate occasions at least 3 months apart)

Psoriatic arthritis

Arthritis plus psoriasis in child – or two out of three of: dactylitis, nail pitting, psoriasis in first-degree relative

Enthesitis-related arthritis

Arthritis and enthesitis – or arthritis or enthesitis and two out of: sacroiliac joint involvement, HLA-B27-positive, male >6 years, acute anterior uveitis, ankylosing spondylitis, inflammatory bowel disease plus sacroilitis in first-degree relative

Undifferentiated arthritis

Arthritis not meeting criteria for one of above categories or fitting more than one of the above groups

  1. Data from Petty and colleagues [2].