Recent developments in anti-rheumatic drugs in pediatrics: treatment of juvenile idiopathic arthritis

Table 3 Criteria for inactive disease and clinical remission in juvenile idiopathic arthritis^a

Criteria
No active synovitis
No fever, rash, serositis, splenomegaly, or generalized lymphadenopathy attributable to juvenile idiopathic arthritis
No active uveitis
Normal erythrocyte sedimentation rate and/or C-reactive protein
Physician's global assessment of disease activity indicates no active disease
Inactive disease
Requires that the patient satisfy all of the above criteria
Clinical remission on medication
Six continuous months of inactive disease on medication
Clinical remission off of medication
12 continuous months of inactive disease off all anti-arthritis and anti-uveitis medications

^aApplies to oligoarticular, polyarticular (rheumatoid factor-negative, rheumatoid factor-positive) and systemic juvenile idiopathic arthritis at this time.
Table reproduced with permission from Ringold S, Wallace CA: Measuring clinical response and remission in juvenile idiopathic arthritis. Curr Opin Rheumatol 2007, 19:471–476 [9]. Data from Wallace and collegues [52].