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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Insights into endocrine-immunological disturbances in autoimmunity and their impact on treatment

Figure 3

Altered balance between nocturnal hormones in rheumatoid arthritis. The altered balance between nocturnal hormone production in chronic diseases such as rheumatoid arthritis (RA) is characterized by increased levels and steady-state duration of melatonin (enhancer of the immune/inflammatory reaction) and by decreased adrenal cortisol availability (downregulator of the immune/inflammatory reaction).

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