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Table 1 Studies evaluating the risk of coronary heart disease in rheumatoid arthritis

From: The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus

[Reference] (year) Study design RA definition n Estimated risk
[18] (2001) Prospective cohort ACR 1987 criteria 236 3.86-fold of combined CV events (MI + revascularization + stroke)
[4] (2003) Prospective cohort ACR 1987 criteria 525 2-fold risk for MI
1.48-fold risk for stroke
RA >10 years: 3-fold risk for MI
[84] (2003) Cross-sectional survey Rheumatologist diagnosis 9,093 2.15-fold risk for MI
[19] (2003) Prospective cohort Physician diagnosis 11,633 1.6-fold risk for MI
[5] (2005) Retrospective cohort ACR 1987 criteria 603 2-fold risk for MI
6-fold risk for unrecognized MI
2-fold risk sudden death
[85] (2007) Retrospective cohort ACR 1987 criteria 239 0.1% to 0.3%/year MI
0.07%/year stroke
[2] (2008) Retrospective cohort Rheumatologist diagnosis 4,363 3.2% prevalence MI
1.9% prevalence stroke
  1. ACR, American College of Rheumatology; CHD, coronary heart disease; CVD, cardiovascular disease; MI, myocardial infarction; RA, rheumatoid arrthritis.