Table 2 Studies evaluating the risk of coronary heart disease in systemic lupus erythematosus
[Reference] (year) | Study design | SLE definition | n | Estimated risk |
|---|---|---|---|---|
[11] (1997) | Prospective cohort | ACR criteria for SLE | 498 | 5-fold risk for MI 50-fold risk in ages 35 to 44 years |
[86] (1999) | Retrospective cohort | Rheumatologist diagnosis | 8,742 | 2.27-fold risk for MI 3.8-fold risk for chronic heart failure |
[12] (2001) | Retrospective cohort | Rheumatologist diagnosis | 296 | 17.0-fold risk for CVD 10.1-fold risk for MI 7.9-fold risk for stroke |
[87] (2004) | Cross-sectional, prospective | ACR criteria for SLE | 202 (cross-sectional), 47 (prospective) | 1.4-fold risk for CHD 0.6-fold risk for stroke 8.5% CHD events 10% stroke follow up |
[88] (2004) | Case control | Physician diagnosis | 770 | 1.46 risk for MI |