Variable | Corticosteroid therapy vs. no corticosteroid therapy | Immunosuppressive therapy vs. no immunosuppressive therapy | ||||
---|---|---|---|---|---|---|
Odds ratio | 95% confidence interval | P value | Odds ratio | 95% confidence interval | P value | |
Subspecialties (rheumatology vs. dermatology) | 1.54 | 1.19 to 1.98 | 0.001 | 2.46 | 1.88 to 3.21 | <0.0001 |
Gender (female vs. male) | 0.69 | 0.51 to 0.96 | 0.025 | 0.78 | 0.56 to 1.10 | 0.13 |
Age (years) | 0.99 | 0.99 to 1.01 | 0.67 | 0.99 | 0.98 to 1.00 | 0.04 |
Systemic sclerosis subsets | ||||||
Limited cutaneous systemic sclerosis (reference group) | 1.00 | 1.00 | ||||
Diffuse cutaneous systemic sclerosis | 1.47 | 0.45 to 4.88 | 0.53 | 1.77 | 0.51 to 6.19 | 0.37 |
Overlap syndrome | 3.64 | 1.06 to 12.51 | 0.04 | 3.69 | 1.02 to 13.37 | 0.05 |
Organ involvement | ||||||
Pulmonary hypertension | 0.83 | 0.59 to 1.17 | 0.30 | 0.94 | 0.66 to 1.35 | 0.73 |
Pulmonary fibrosis | 2.30 | 1.77 to 2.99 | <0.0001 | 1.53 | 1.16 to 2.00 | 0.002 |
Musculoskeletal system | 1.40 | 1.08 to 1.81 | 0.01 | 1.31 | 1.00 to 1.71 | 0.05 |
Esophagus | 1.01 | 0.78 to 1.29 | 0.96 | 0.92 | 0.70 to 1.20 | 0.53 |
Kidney | 1.66 | 1.12 to 2.47 | 0.01 | 0.91 | 0.59 to 1.38 | 0.64 |
Heart | 1.28 | 0.91 to 1.81 | 0.16 | 1.34 | 0.93 to 1.92 | 0.12 |