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Table 2 Multivariate relationship of corticosteroid and immunosuppressive agent use with subspecialty, disease subset and organ involvement

From: High frequency of corticosteroid and immunosuppressive therapy in patients with systemic sclerosis despite limited evidence for efficacy

Variable Corticosteroid therapy vs. no corticosteroid therapy Immunosuppressive therapy vs. no immunosuppressive therapy
  Odds ratio 95% confidence interval P value Odds ratio 95% confidence interval P value
Subspecialties (rheumatology vs. dermatology) 1.54 1.19 to 1.98 0.001 2.46 1.88 to 3.21 <0.0001
Gender (female vs. male) 0.69 0.51 to 0.96 0.025 0.78 0.56 to 1.10 0.13
Age (years) 0.99 0.99 to 1.01 0.67 0.99 0.98 to 1.00 0.04
Systemic sclerosis subsets       
   Limited cutaneous systemic sclerosis (reference group) 1.00    1.00   
   Diffuse cutaneous systemic sclerosis 1.47 0.45 to 4.88 0.53 1.77 0.51 to 6.19 0.37
   Overlap syndrome 3.64 1.06 to 12.51 0.04 3.69 1.02 to 13.37 0.05
Organ involvement       
   Pulmonary hypertension 0.83 0.59 to 1.17 0.30 0.94 0.66 to 1.35 0.73
   Pulmonary fibrosis 2.30 1.77 to 2.99 <0.0001 1.53 1.16 to 2.00 0.002
   Musculoskeletal system 1.40 1.08 to 1.81 0.01 1.31 1.00 to 1.71 0.05
   Esophagus 1.01 0.78 to 1.29 0.96 0.92 0.70 to 1.20 0.53
   Kidney 1.66 1.12 to 2.47 0.01 0.91 0.59 to 1.38 0.64
   Heart 1.28 0.91 to 1.81 0.16 1.34 0.93 to 1.92 0.12