Skip to main content

Table 2 Relationship between adiposity measures and risk of primary joint replacement

From: Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study

Variable

Number of cases in each quartile

Hazard ratio

95% confidence interval

P value

Weight (kg)

    

   Q1 (F <59.7, M <73.0)

136 (9,756)

1.00

  

   Q2 (F 59.7 to 66.2, M 73.0 to 79.7)

202 (9,485)

1.58

1.27 to 1.97

 

   Q3 (F 66.2 to 74.6, M 79.7 to 87.4)

269 (9,418)

2.17

1.77 to 2.67

 

   Q4 (F >74.6, M >87.4)

401 (9,329)

3.44

2.83 to 4.18

 

   Linear model (per 10 kg)

 

1.42

1.36 to 1.48

<0.001

Body mass index (kg/m2)

    

   Q1 (F <23.2, M <24.7)

128 (9,663)

1.00

  

   Q2 (F 23.2 to 25.9, M 24.7 to 26.8)

211 (9,511)

1.65

1.32 to 2.05

 

   Q3 (F 25.9 to 29.3, M 26.8 to 29.2)

302 (9,458)

2.48

2.01 to 3.05

 

   Q4 (F >29.3, M >29.2)

367 (9,354)

3.44

2.80 to 4.22

 

   Linear model (per 5 kg/m2)

 

1.60

1.51 to 1.70

<0.001

Waist circumference (cm)

    

   Q1 (F <71.0, M <87.0)

136 (9,943)

1.00

  

   Q2 (F 71.0 to 78.0, M 87.0 to 93.0)

222 (9,612)

1.59

1.29 to 1.97

 

   Q3 (F 78.0 to 87.0, M 93.0 to 99.0)

290 (9,399)

2.07

1.68 to 2.54

 

   Q4 (F >87.0, M >99.0)

360 (9,025)

2.77

2.26 to 3.39

 

   Linear model (per 10 cm)

 

1.38

1.31 to 1.45

<0.001

Waist-to-hip ratio

    

   Q1 (F < 0.74, M < 0.88)

193 (9,553)

1.00

  

   Q2 (F 0.74 to 0.78, M 0.88 to 0.92)

234 (9,516)

1.13

0.94 to 1.37

 

   Q3 (F 0.78 to 0.82, M 0.92 to 0.96)

264 (9,498)

1.23

1.02 to 1.48

 

   Q4 (F > 0.82, M > 0.96)

317 (9,410)

1.46

1.21 to 1.76

 

   Linear model (per 0.1 unit)

 

1.23

1.12 to 1.35

<0.001

Fat mass (kg)

    

   Q1 (F <21.1, M <18.4)

125 (9,586)

1.00

  

   Q2 (F 21.1 to 26.5, M 18.4 to 23.0)

209 (9,502)

1.71

1.37 to 2.13

 

   Q3 (F 26.5 to 32.9, M 23.0 to 27.9)

273 (9,438)

2.26

1.83 to 2.80

 

   Q4 (F >32.9, M >27.9)

398 (9,312)

3.51

2.87 to 4.30

 

   Linear model (per 10 kg)

 

1.61

1.52 to 1.71

<0.001

Percentage fat (%)

    

   Q1 (F <35.3, M <25.0)

143 (9,568)

1.00

  

   Q2 (F 35.3 to 40.1, M 25.0 to 28.9)

205 (9,506)

1.45

1.17 to 1.80

 

   Q3 (F 40.1 to 44.6, M 28.9 to 32.6)

260 (9,451)

1.86

1.51 to 2.28

 

   Q4 (F >44.6, M >32.6)

397 (9,313)

2.99

2.46 to 3.63

 

   Linear model (per 10%)

 

2.01

1.81 to 2.22

<0.001

  1. All models using sex-specific quartiles of adiposity measures adjusted for age, gender, country of birth, and highest level of education. All models using continuous adiposity measures adjusted for age, country of birth, and highest level of education, stratifying by gender, representing an approximate change of one standard deviation for each of the adiposity measures. Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile; F, female; M, male.
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us