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Figure 4 | Arthritis Research & Therapy

Figure 4

From: The effects of infliximab therapy on the serum proteome of rheumatoid arthritis patients

Figure 4

Ingenuity pathway analysis of proteins displaying alterations in expression patterns following infliximab treatment in patients deemed to be non-responders. (See Results for response definitions.) A network analysis of the differentially expressed proteins in the non-responder group indicates that, as with the responder network shown in Figure 2, tumour necrosis factor (TNF) is at the centre of the network but the down-regulated proteins are more distal, whereas more proximal proteins such as C-reactive protein (CRP) are up-regulated.

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