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Table 2 Change in total (L+D) amino acid composition with age in normal cartilage, osteoarthritic articular, and meniscal cartilages

From: Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages

   Amino acid
   Asx Ser Leu Ile Glx Ala
Normal articular cartilage Mean (nmol/mg) 157.3 104.8 87.4 37.2 252.5 262
  r 2 0.054 0.037 0.042 0.065 0.060 0.090
  Slope -0.456 -0.233 -0.203 -0.120 -0.796 -1.040
  P value 0.327 0.418 0.399 0.293 0.297 0.198
OA articular cartilage Mean (nmol/mg) 99.5 67.7 56.0 23.2 159.1 165.7
  r 2 0.076 0.070 0.028 0.081 0.056 0.059
  Slope 0.419 0.278 0.237 0.196 0.532 0.645
  P value 0.141 0.157 0.377 0.129 0.208 0.196
OA meniscal cartilage Mean (nmol/mg) 100.4 74.6 53.4 23.7 140.5 180.4
  r 2 0.208 0.194 0.143 0.144 0.194 0.232
  Slope -1.11 -0.78 -1.06 -0.458 -1.59 -2.57
  P value 0.011a 0.015a 0.040a 0.039a 0.015a 0.007a
  1. Composition is presented in nanomoles per milligram of tissue wet weight. aDenotes significant value. Ala, alanine; Asx, asparagine + aspartate; Glx, glutamate + glutamine; Ile, isoleucine; Leu, leucine; OA, osteoarthritic; Ser, serine.