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Table 1 Demographic details, cardiovascular risk factors, features of rheumatoid arthritis (RA) and its control in the study population (n = 138)

From: Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis

Parameter

Value

Demographics:

 

   Age (years)

64.0 (10.9)

   Females, n (%)

92 (66.7)

   Duration of RA (years)

17.6 (13.6)

   RF positive, n (%)

83 (61.0)

CV disease:

 

   History of MI, n (%)

14 (10.1)

   History of angina, n (%)

11 (8.0)

   History of stroke/TIA, n (%)

9 (6.5)

   History of PVD, n (%)

6 (4.4)

   Any vascular event, n (%)

26 (18.8)

Risk factors for CV diseases:

 

   Smoking pack-year history

18 (24)

   Current smoker, n (%)

25 (18.1)

   History of hypertension, n (%)

47 (34.1)

   History of hyperlipidemia, n (%)

33 (23.9)

   History of diabetes, n (%)

19 (13.8)

   Family history CV disease, n (%)

38 (27.5)

Clinical findings:

 

   BMI (kg/m2)

27.5 (6.9)

   Systolic BP (mmHg)

132 (19)

   Diastolic BP (mmHg)

78 (10)

Laboratory tests:

 

   ESR (mm/h)

25 (18)

   CRP (mg/l)

13.6 (18.6)

   Total cholesterol (mmol/l)

5.3 (1.0)

   HDL cholesterol (mmol/l)

1.5 (0.4)

   LDL cholesterol (mmol/l)

3.0 (0.9)

   TG (mmol/l)

1.6 (1.0)

   Homocysteine (μmol/l)

12 (5)

   Fasting glucose (mmol/l)

5.6 (1.6)

   Serum creatinine (mmol/l)

0.08 (0.05)

   CrCl (ml/min)

79.1 (29.9)

   Framingham score (%)

11.1 (9.5)

   ECG evidence of ischemia, n (%)

2 (1.5)

Severity and feature of RA:

 

   Radiographic erosion score

24 (35)

   Joint space narrowing score

21 (28)

   Presence of erosive disease, n (%)

97 (71.3)

   History of vasculitis, n (%)

15 (10.9)

   Shared epitope, n (%)

103 (75.2)

   > 10 mg/day of prednisone, n (%)

9 (6.5)

   RAGE polymorphism, n (%)

29 (21.0)

  1. BP, blood pressure; CrCl, creatinine clearance; CRP < C-reactive protein; CV, cardiovascular; ECG, electrocardiogram; ESR, erythrocyte sedimantation rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MI, myocardial infarction; PVD, peripheral vascular disease; RAGE, receptor for advanced glycation end products; RF, rheumatoid factor; TG, triglyceride; TIA, transient ischemic attack.