Subchondral bone and calcified cartilage. Representative sections and data of placebo-treated and ASU-treated dogs 8 weeks post-surgery (original magnification ×100). Sections were stained with haematoxylin/eosin. Data for bone volume and calcified cartilage thickness are represented as box plot and were analyzed using Student's unpaired t-test. P ≤ 0.05 is considered significant. ASU, avocado/soybean unsaponifiables.