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Table 1

From: Infiltrate analysis of rheumatoid synovial tissue before and after high does chemotherapy and autologous stem cell transplantation

 

Responders

Non-responders

 
 

Before

After

Before

After

P *

CD 3

2.8 ± 0.5

1.3 ± 2.3

1.0 ± 1.4

1.7 ± 2.1

0.06

CD27

3.0 ± 0.8

0.3 ± 0.6

1.0 ± 0.8

1.7 ± 2.1

0.05

CD45RA

2.3 ± 0.9

0.7 ± 1.2

0.5 ± 1

1.6 ± 2.1

0.03

CD45RO

3.4 ± 0.5

0.7 ± 1.2

1.8 ± 1.6

2.0 ± 2

0.04

CD45RB

3.2 ± 0.8

1.0 ± 1.7

2.0 ± 1.6

2.0 ± 2.0

0.05

  1. Mean Histological Score ± STDEV. * Mann-Whitney U test. Clinical and immunohistochemical responses were predicted by CD27 (P = 0.016), CD45RO (P = 0.003) and CD45RB (P = 0.047) infiltration before treatment.
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Arthritis Research & Therapy

ISSN: 1478-6362

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