Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility

Table 1 Comparison of allele frequencies in the tag-SNPs covering variability in the TNFAIP3 gene

SNP	MAF (% [n/N])	OR (95% CI)	P
rs600144
Cases	25.9 (850/3278)	0.96 (0.9 to 1.1)	NS
Controls	26.8 (857/3202)
rs11970361
Cases	5.7 (187/3300)	0.94 (0.8 to 1.2)	NS
Controls	6.0 (194/3238)
rs11970411
Cases	10.2 (338/3300)	1.01 (0.9 to 1.2)	NS
Controls	10.1 (328/3238)
rs582757
Cases	24.8 (816/3286)	0.89 (0.8 to 0.99)	0.041
Controls	27.0 (871/3220)
rs17780429
Cases	12.7 (418/3300)	0.91 (0.8 to 1.0)	NS
Controls	13.8 (446/3236)

Shown is a comparison of the allele frequencies in the tag-single nucleotide polymorphisms (SNPs) covering variability in the TNFAIP3 gene between patients with rheumatoid arthritis (cases) and control individuals (controls). MAF, minor allele frequency; n, number of minor alleles; N, total number of alleles.

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