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Table 2 Distribution of estimated haplotype frequencies in the TNFAIP3 locus

From: Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility

Haplotype # rs600144 rs11970361 rs11970411 rs582757 rs17780429 Controls (n [%]) Cases (n [%]) OR (95% CI)
1 T C G C A 427 (13.2%) 399 (12.1%) 0.92 (0.79 to 1.06)
2 T T C T G 185 (5.7%) 175 (5.3%) 0.93 (0.76 to 1.16)
3 T C G C G 443 (13.7%) 420 (12.7%) 0.93 (0.81 to 1.07)
4 C C G T G 849 (26.2%) 843 (25.5%) 0.98 (0.88 to 1.09)
5 T C G T G 1,159 (35.8%) 1,271 (38.5%) 1.14 (1.03 to 1.26)
6 T C C T G 141 (4.4%) 162 (4.9%) 1.15 (0.91 to 1.44)
  1. Distribution of estimated haplotype frequencies in the TNFAIP3 locus for control individuals (controls) and patients with rheumatoid arthritis (cases). The minor allele of each tag-single nucleotide polymorphism is presented in bold. Haplotypes with frequency over 2% are shown, ordered by the odds ratio (OR) comparing cases with controls. Haplotype #5 was significantly different. CI, confidence interval.