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Table 4 Allele frequency differences in tagSNPs of the intergenic 6q23 region: ACPA-positive cases versus controls

From: Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility

SNP MAF% (n/N) OR (95%CI) P
rs566097    
   ACPA+ cases 10.9 (84/772) 0.94 (0.7 to 1.2) NS
   Controls 11.5 (367/3,190)   
rs13207033    
   ACPA+ cases 25.1 (185/736) 0.80 (0.66 to 0.96) 0.015
   Controls 29.7 (914/3,082)   
rs489738    
   ACPA+ cases 18.2 (138/760) 0.97 (0.8 to 1.2) NS
   Controls 18.6 (586/3,158)   
rs12194935    
   ACPA+ cases 26.1 (198/758) 1.18 (1.0 to 1.4) NS
   Controls 23.0 (726/3,154)   
rs536331    
   ACPA+ cases 37.9 (292/770) 0.83 (0.71 to 0.97) 0.023
   Controls 42.4 (1,351/3,184)   
rs675520    
   ACPA+ cases 44.5 (334/750) 0.82 (0.70 to 0.96) 0.014
   Controls 49.5 (1,520/3,070)   
rs6920220    
   ACPA+ cases 22.3 (172/770) 1.15 (0.95 to 1.39) NS
   Controls 20.1 (639/3,184)   
rs694069    
   ACPA+ cases 35.5 (273/770) 0.82 (0.70 to 0.97) 0.019
   Controls 40.1 (1,276/3,186)   
rs6917441    
   ACPA+ cases 27.9 (212/760) 1.11 (0.9 to 1.3) NS
   Controls 25.8 (816/3,166)   
rs647108    
   ACPA+ cases 41.9 (321/766) 1.04 (0.9 to 1.2) NS
   Controls 41.0 (1,306/3,184)   
  1. Allele frequency differences in tag-single nucleotide polymorphism (SNP) of the intergenic 6q23 region between patients with rheumatoid arthritis positive for anti-citrullinated peptide antibodies (ACPA+ cases) and control individuals (controls). MAF, minor allele frequency; n, number of minor alleles; N, total number of alleles.