Skip to main content

Table 1 Examples of comorbid conditions by their relationship with rheumatoid arthritis

From: Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases

Estimated relationship to RA Comorbid condition Mechanism of relationship
High Anemia RA activity
  Osteoporosis CS, RA, decreased function
  Bacterial infection RA, CS, smoking, (TNF?)
Medium Lymphoma RA activity, (TNF?)
  GI ulceration NSAIDs, CS
  Myocardial infarction RA, CS
  Heart failure RA, CS
Low Stroke RA
  Depression Chronic pain
  Fracture CS, decreased function
  Skin cancer RA, TNF
  Any cancer  
No relationship Appendicitis  
  1. CS, corticoid steroid treatment, GI, gastrointestinal; NSAID = Non-steroidal anti-inflammatory drug treatment; RA, rheumatoid arthritis; TNF, antitumor necrosis factor treatment.