Skip to main content

Table 2 Mean analyte concentrations in cartilage extracts

From: Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate

Cartilage region

Number

IsoAsp μM/g cartilage ± SEM

Protein μg/g cartilage ± SEM

GAG μg/g cartilage ± SEM

Normal

8

7,092 ± 1,568

65,092 ± 18,017

743 ± 102

Lesioned OA

14

4,942 ± 719

15,281 ± 552a

4,463 ± 1,053b

Non-lesioned OA

14

7,439 ± 1,273

17,926 ± 1,134c

2,911 ± 657b

Superficial

6

2,453 ± 315c

11,266 ± 818c

3,626 ± 921

Deep

6

3,999 ± 665d

16,894 ± 3,105c

7,316 ± 1,279a, d, e

  1. aP < 0.001 compared to normal cartilage; bP < 0.01 compared to normal cartilage; cP < 0.05 compared to normal cartilage; dP < 0.05 compared to superficial cartilage; eP < 0.05 compared to osteoarthritis (OA) lesion cartilage. GAG, glycosaminoglycan; IsoAsp, isomerized aspartate; SEM, standard error of the mean.