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Table 2 Mean analyte concentrations in cartilage extracts

From: Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate

Cartilage region Number IsoAsp μM/g cartilage ± SEM Protein μg/g cartilage ± SEM GAG μg/g cartilage ± SEM
Normal 8 7,092 ± 1,568 65,092 ± 18,017 743 ± 102
Lesioned OA 14 4,942 ± 719 15,281 ± 552a 4,463 ± 1,053b
Non-lesioned OA 14 7,439 ± 1,273 17,926 ± 1,134c 2,911 ± 657b
Superficial 6 2,453 ± 315c 11,266 ± 818c 3,626 ± 921
Deep 6 3,999 ± 665d 16,894 ± 3,105c 7,316 ± 1,279a, d, e
  1. aP < 0.001 compared to normal cartilage; bP < 0.01 compared to normal cartilage; cP < 0.05 compared to normal cartilage; dP < 0.05 compared to superficial cartilage; eP < 0.05 compared to osteoarthritis (OA) lesion cartilage. GAG, glycosaminoglycan; IsoAsp, isomerized aspartate; SEM, standard error of the mean.