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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Differential gene expression in the salivary gland during development and onset of xerostomia in Sjögren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2mouse

Figure 5

Differential expression of genes reported to be associated with connective tissue autoimmunity in humans and/or mouse models. Temporal changes in gene expressions in the salivary glands of C57BL/6.NOD-Aec1Aec2 mice for genes that are reportedly associated with Sjögren's syndrome, systemic lupus erythematosus, and/or rheumatoid arthritis in humans (a, b) and genes considered important for disease development in the salivary glands of non-obese diabetic (NOD) and NOD-derived mice (c, d). Expression profiles are presented for these genes at 8, 12, 16, and 20 weeks of age relative to 4 weeks of age. Aec, autoimmunexocrinopathy.

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