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Table 1 Pathways represented in 480 differentially expressed genes with highest statistical discrimination

From: Differential gene expression in the salivary gland during development and onset of xerostomia in Sjögren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2mouse

Classifications

Number of genes

Percentage of genes

P value

Pathways

   

Integrin signaling pathway (P00034)

21

4.60%

9.92 × 10-10

Vitamin B6 metabolism (P02787)

3

0.70%

3.53 × 10-5

p53 pathway (P00059)

10

2.20%

4.77 × 10-5

Cell cycle (P00013)

4

0.90%

0.000843

Muscarinic acetylcholine receptor 2 and 4 signaling pathway (P00043)

5

1.10%

0.002843

Muscarinic acetylcholine receptor 1 and 3 signaling pathway (P00042)

4

0.90%

0.018809

Angiogenesis (P00005)

9

2.00%

0.019019

Metabotropic glutamate receptor group I pathway (P00041)

3

0.70%

0.020464

FGF signaling pathway (P00021)

6

1.30%

0.023515

Hedgehog signaling pathway (P00025)

3

0.70%

0.028308

VEGF signaling pathway (P00056)

4

0.90%

0.033627

PI3 kinase pathway (P00048)

5

1.10%

0.039324

  1. FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor.