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Table 1 Comparison of rheumatoid arthritis patients and controls on pain and questionnaire responses

From: Enhanced reactivity to pain in patients with rheumatoid arthritis

  RA patients
(n = 19)
Controls
(n = 21)
P value
Responses to noxious stimuli
   HPTh, °C 41.4 ± 5.1 44.4 ± 4.5 0.05
   PPTh on leg, kPa 665.5 ± 287.7 811.3 ± 400.1 0.19
   PPTh on thumb, kPa 295.7 ± 141.6 395.7 ± 150.7 0.03
   PPTh on trapezius, kPa 404.5 ± 160.7 536.2 ± 276.9 0.08
   Cold pain rating (0 to 100) at midpoint 82.3 ± 12.6 65.4 ± 25.6 0.01
   Cold pain rating (0 to 100) at conclusion 83.0 ± 12.4 67.7 ± 24.8 0.02
   Cold pain tolerance, seconds 61.8 ± 54.1 111.8 ± 63.8 0.01
   Heat pain rating at 49°C 74.4 ± 25.1 57.7 ± 34.7 0.09
   Heat pain rating at 51°C 86.8 ± 16.2 68.2 ± 32.4 0.03
   Painful heat after-sensations 16.8 ± 23.2 5.7 ± 9.4 0.05
Questionnaire data
   Current pain (0 to 10) 3.2 ± 2.3 0.4 ± 0.3 < 0.001
   Current stress (0 to 10) 2.2 ± 2.4 1.2 ± 1.9 0.17
   Beck Depression Inventory score 7.0 ± 6.3 2.5 ± 3.0 0.01
   SF-36, subscale score    
General health 52.9 ± 20.3 84.0 ± 19.4 < 0.001
Physical functioning 42.1 ± 24.2 69.1 ± 26.7 0.002
Physical role 28.9 ± 31.5 86.9 ± 28.1 < 0.001
Bodily pain 44.2 ± 21.3 85.7 ± 23.7 < 0.001
Energy/fatigue 53.4 ± 18.4 67.6 ± 18.1 0.02
Mental health 80.7 ± 13.7 81.0 ± 14.5 0.95
Emotional role 84.2 ± 34.0 93.7 ± 22.7 0.30
Social functioning 70.4 ± 27.7 94.6 ± 7.5 0.001
  1. Data are presented as mean ± standard deviation. HPTh, heat pain threshold; PPTh, pressure pain threshold; RA, rheumatoid arthritis; SF-36, Short Form Health Survey-36.