Figure 3
From: Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis
Antibody concentrations. Course of (a) rheumatoid factor (RF), (b) cyclic citrullinated peptide (CCP) antibodies, and (c) total immunoglobulin IgG, IgA, and IgM serum concentrations after therapeutic B-cell depletion in good responders (continuous line) and in non-responders or moderate responders (designated as other patients, dotted line). Asterisks indicate statistically significant differences (P < 0.05) between these two patient groups.