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Table 4 Subset analysis showing genetic association between clinical subsets of patients with Behçet's disease compared with normal healthy controls

From: Identification of novel genetic susceptibility loci for Behçet's disease using a genome-wide association study

Clinical subset SNP Associated allele OR 95% confidence interval P value
     LL UL  
Eye disease present rs11206377 G 1.81 1.13 2.90 0.0125
  rs2061634 G 1.82 1.14 2.89 0.011
  rs317711 C 2.31 1.34 3.98 0.0023
  rs4936742 T 2.17 1.37 3.44 0.0008
  rs9513584 G 1.05 0.65 1.69 0.8403
Eye disease absent rs11206377 G 1.96 1.33 2.89 0.0007
  rs2061634 G 2.26 1.54 3.33 3.01 × 10-5
  rs317711 C 2.26 1.41 3.63 0.0006
  rs4936742 T 1.40 0.96 2.04 0.0823
  rs9513584 G 1.97 1.34 2.88 0.0005
Vascular disease present rs11206377 G 2.01 1.18 3.40 0.009
  rs2061634 G 1.47 0.88 2.46 0.1385
  rs317711 C 2.20 1.21 3.99 0.0087
  rs4936742 T 2.04 1.23 3.36 0.0049
  rs9513584 G 1.74 1.05 2.86 0.0292
Vascular disease absent rs11206377 G 1.86 1.29 2.70 0.001
  rs2061634 G 2.35 1.62 3.43 6.22 × 10-6
  rs317711 C 2.25 1.42 3.57 0.0004
  rs4936742 T 1.54 1.07 2.21 0.0209
  rs9513584 G 1.52 1.04 2.20 0.0281
Both eye and vascular disease present rs11206377 G 3.11 1.29 7.47 0.0082
  rs2061634 G 1.37 0.66 2.88 0.3987
  rs317711 C 3.29 1.52 7.12 0.0015
  rs4936742 T 2.39 1.14 5.02 0.0184
  rs9513584 G 1.24 0.60 2.59 0.5585
Neither eye nor vascular disease present rs11206377 G 2.10 1.36 3.24 0.0007
  rs2061634 G 2.59 1.70 3.95 7.16 × 10-6
  rs317711 C 2.50 1.51 4.14 0.0003
  rs4936742 T 1.30 0.86 1.98 0.2123
  rs9513584 G 1.84 1.21 2.79 0.0042
  1. LL, lower limit; OR, odds ratio; SNP, single-nucleotide polymorphism; UL, upper limit.