|
Clinical subset
|
SNP
|
Associated allele
|
OR
|
95% confidence interval
|
P value
|
|---|
| | | | |
LL
|
UL
| |
|---|
|
Eye disease present
|
rs11206377
|
G
|
1.81
|
1.13
|
2.90
|
0.0125
|
| |
rs2061634
|
G
|
1.82
|
1.14
|
2.89
|
0.011
|
| |
rs317711
|
C
|
2.31
|
1.34
|
3.98
|
0.0023
|
| |
rs4936742
|
T
|
2.17
|
1.37
|
3.44
|
0.0008
|
| |
rs9513584
|
G
|
1.05
|
0.65
|
1.69
|
0.8403
|
|
Eye disease absent
|
rs11206377
|
G
|
1.96
|
1.33
|
2.89
|
0.0007
|
| |
rs2061634
|
G
|
2.26
|
1.54
|
3.33
|
3.01 × 10-5
|
| |
rs317711
|
C
|
2.26
|
1.41
|
3.63
|
0.0006
|
| |
rs4936742
|
T
|
1.40
|
0.96
|
2.04
|
0.0823
|
| |
rs9513584
|
G
|
1.97
|
1.34
|
2.88
|
0.0005
|
|
Vascular disease present
|
rs11206377
|
G
|
2.01
|
1.18
|
3.40
|
0.009
|
| |
rs2061634
|
G
|
1.47
|
0.88
|
2.46
|
0.1385
|
| |
rs317711
|
C
|
2.20
|
1.21
|
3.99
|
0.0087
|
| |
rs4936742
|
T
|
2.04
|
1.23
|
3.36
|
0.0049
|
| |
rs9513584
|
G
|
1.74
|
1.05
|
2.86
|
0.0292
|
|
Vascular disease absent
|
rs11206377
|
G
|
1.86
|
1.29
|
2.70
|
0.001
|
| |
rs2061634
|
G
|
2.35
|
1.62
|
3.43
|
6.22 × 10-6
|
| |
rs317711
|
C
|
2.25
|
1.42
|
3.57
|
0.0004
|
| |
rs4936742
|
T
|
1.54
|
1.07
|
2.21
|
0.0209
|
| |
rs9513584
|
G
|
1.52
|
1.04
|
2.20
|
0.0281
|
|
Both eye and vascular disease present
|
rs11206377
|
G
|
3.11
|
1.29
|
7.47
|
0.0082
|
| |
rs2061634
|
G
|
1.37
|
0.66
|
2.88
|
0.3987
|
| |
rs317711
|
C
|
3.29
|
1.52
|
7.12
|
0.0015
|
| |
rs4936742
|
T
|
2.39
|
1.14
|
5.02
|
0.0184
|
| |
rs9513584
|
G
|
1.24
|
0.60
|
2.59
|
0.5585
|
|
Neither eye nor vascular disease present
|
rs11206377
|
G
|
2.10
|
1.36
|
3.24
|
0.0007
|
| |
rs2061634
|
G
|
2.59
|
1.70
|
3.95
|
7.16 × 10-6
|
| |
rs317711
|
C
|
2.50
|
1.51
|
4.14
|
0.0003
|
| |
rs4936742
|
T
|
1.30
|
0.86
|
1.98
|
0.2123
|
| |
rs9513584
|
G
|
1.84
|
1.21
|
2.79
|
0.0042
|
- LL, lower limit; OR, odds ratio; SNP, single-nucleotide polymorphism; UL, upper limit.
