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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts

Figure 2

GusB, Hyal1 and klotho gene expression in arthritis patients' synovial membrane and fibroblast samples. Gene expression for β-D-glucuronidase (GusB), hyaluronidase 1 (Hyal1), and klotho genes was lower in rheumatoid arthritis (RA) and osteoarthritis (OA) synovial fibroblasts (SFs) than in RA and OA synovial membrane (SM) tissue samples (Mann-Whitney rank sum test). The Hyal1 gene expression was significantly higher in OA SM as compared with RA SM (Mann – Whitney rank sum test). The sperm adhesion molecule 1 gene expression was undetectable. Gex, gene expression; HGPRT, hypoxanthine phosphoribosyl transferase. *P < 0.05; **P < 0.01; ***P < 0.001.

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