Figure 2From: Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblastsGusB, Hyal1 and klotho gene expression in arthritis patients' synovial membrane and fibroblast samples. Gene expression for β-D-glucuronidase (GusB), hyaluronidase 1 (Hyal1), and klotho genes was lower in rheumatoid arthritis (RA) and osteoarthritis (OA) synovial fibroblasts (SFs) than in RA and OA synovial membrane (SM) tissue samples (Mann-Whitney rank sum test). The Hyal1 gene expression was significantly higher in OA SM as compared with RA SM (Mann – Whitney rank sum test). The sperm adhesion molecule 1 gene expression was undetectable. Gex, gene expression; HGPRT, hypoxanthine phosphoribosyl transferase. *P < 0.05; **P < 0.01; ***P < 0.001.Back to article page