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Table 1 Characteristics of study sample

From: Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

Variable RA cases
(n = 520)
RA-free OA controls
(n = 303)
P
Gender, % female (n) 83.3 (433) 80.2 (243) ns
Age at inclusion, years (range) 51.6 ± 11.2 (19 to 80) 57.9 ± 13.5 (21 to 83) < 0.0001
Age of onset, years 40.8 ± 12.7 50.7 ± 12.8 < 0.0001
Duration of disease, years 10.8 ± 8.3 7.2 ± 6.8 < 0.0001
RF, IU/ml 149.8 ± 67.2 - -
RF-positive, % (n) 53.8 (280) - -
anti-CCP antibody, RU/mla 67.5 ± 53.7 1.5 ± 6.4 < 0.0001
anti-CCP positive, % (n)b 78.6 (239) 3.2 (4) < 0.0001
CRP, μg/ml 19.6 ± 23.7 5.1 ± 9.2 < 0.0001
  1. Values denote means ± standard deviations unless indicated otherwise.
  2. CCP = cyclic citrullinated peptide; CRP = C-reactive protein; ns = not significant; RF = rheumatoid factor.
  3. a anti-CCP antibody serum level was determined in 428 individuals.
  4. b Values below 4.2 RU/ml were considered as anti-CCP negative.