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Table 3 Power analysis of SNP markers

From: Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

SNP

Published ORa

Published MAF in controls

Ref

Current study's MAF in controls

Powerb

rs2476601

1.98

0.10

[4]

0.108

94.5%

rs7574865

1.27

0.22

[5]

0.202

35.9%

rs10499194

0.75

0.21 to 0.31

[6]

0.315

53.1%

rs6920220

1.22

0.21 to 0.22

[7]

0.154

23.4%

rs3761847

1.32

0.37 to 0.45

[8]

0.387

57.0%

rs10818488

1.26

0.44

[9]

0.390

44.4%

  1. OR = odds ratio; MAF = minor allele frequency; Ref = reference; SNP = single nucleotide polymorphism.
  2. a combination of initial finding and replication (when available) in the cited study; effects from minor allele.
  3. b Power was calculated for published OR and MAF in controls from the present study (Table 4) with 520 cases and 303 controls assuming a one-tailed P = 0.05.