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Table 4 SNP characteristics in RA-OA case-control sample

From: Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

 

RA case genotypes

RA-free OA control genotypes

SNP

11

12

22

MAF

P (HWE)

11

12

22

MAF

P (HWE)

rs2476601

356

144

14

0.167

1

239

61

2

0.108

0.551

rs7574865

259

205

54

0.302

0.175

196

87

17

0.202

0.104

rs10499194

281

200

37

0.264

0.910

149

116

37

0.315

0.062

rs6920220

324

175

16

0.201

0.218

213

78

7

0.154

1

rs3761847

186

243

87

0.404

0.648

117

133

49

0.387

0.275

rs10818488

186

240

85

0.401

0.645

116

134

50

0.390

0.278

  1. HWE = Hardy-Weinberg equilibrium; MAF = minor allele frequency; OA = osteoarthritis; RA = rheumatoid arthritis; SNP = single nucleotide polymorphism. Numbers of genotypes (11, 12, 22) according to alleles from Table 2.
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Arthritis Research & Therapy

ISSN: 1478-6362

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