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Table 5 SNP association analysis results in RA-OA case-control sample

From: Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

 

Allelic

Allelic

Allelic OR

 

SNP

P

P corr.a

(95% CI)

Locus

rs2476601

9.5 × 10-4

5.7 × 10-3

1.67 (1.23 to 2.26)

PTPN22

rs7574865

9.2 × 10-6

5.5 × 10-5

1.71 (1.35 to 2.18)

STAT4

rs10499194

0.030

0.180

0.78 (0.63 to 0.98)

OLIG3/TNFAIP3

rs6920220

0.019

0.114

1.38 (1.05 to 1.80)

OLIG3/TNFAIP3

rs3761847

0.480

1

1.08 (0.88 to 1.32)

TRAF1/C5

rs10818488

0.657

1

1.05 (0.85 to 1.29)

TRAF1/C5

  1. a Bonferroni correction for six SNPs tested.
  2. CI = confidence interval; OA = osteoarthritis; OR = odds ratio; RA = rheumatoid arthritis; SNP = single nucleotide polymorphism.
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Arthritis Research & Therapy

ISSN: 1478-6362

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