Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

Table 6 HLA-DRB1 allele distribution in RA-OA case-control sample

	RA case genotypes^b					RA-free OA control genotypes^b
HLA-DRB1 allele^a	0	1	2	MAF	P (HWE)	0	1	2	MAF	P (HWE)
*01	350	139	7	0.154	0.121	223	75	1	0.129	0.040
*03	412	81	3	0.088	1	251	45	3	0.085	0.459
*04	268	192	36	0.266	0.819	234	64	1	0.110	0.229
*07	414	82	0	0.083	0.038	224	69	6	0.136	0.804
*08	471	25	0	0.025	1	279	20	0	0.033	1
*09	485	11	0	0.011	1	296	3	0	0.005	1
*10	466	30	0	0.030	1	294	5	0	0.008	1
*11	403	88	5	0.099	0.804	229	68	2	0.120	0.279
*12	486	10	0	0.010	1	282	17	0	0.028	1
*13	434	59	3	0.066	0.457	226	69	4	0.129	0.799
*14	475	21	0	0.021	1	283	15	1	0.028	0.209
*15	417	74	5	0.085	0.381	228	68	3	0.124	0.593
*16	435	60	1	0.063	0.711	262	36	1	0.064	1

^a Allele numbering according to Table S1 in Additional data file 1.
^b Numbers indicate counts of rare alleles.
HWE = Hardy-Weinberg equilibrium; MAF = minor allele frequency; OA = osteoarthritis; RA = rheumatoid arthritis.

ISSN: 1478-6362