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Table 7 HLA-DRB1 allele association analysis results in RA-OA case-control sample

From: Association of common polymorphisms in known susceptibility genes with rheumatoid arthritis in a Slovak population using osteoarthritis patients as controls

 

Allelic

Allelic OR

 

HLA-DRB1 allelea

P

(95% CI)

Classificationb

*01

0.162

1.25 (0.92 to 1.66)

N

*03

0.868

1.03 (0.72 to 1.48)

N

*04

1.2 × 10-13

2.92 (2.18 to 3.91)

SE

*07

7.7 × 10-4

0.58 (0.41 to 0.80)

P

*08

0.337

0.75 (0.41 to 1.36)

N

*09

0.209

2.22 (0.62 to 8.00)

N

*10

4.0 × 10-3

3.70 (1.43 to 9.59)

SE

*11

0.177

0.81 (0.58 to 1.11)

N

*12

6.1 × 10-3

0.35 (0.16 to 0.77)

P

*13

1.8 × 10-5

0.47 (0.34 to 0.67)

P

*14

0.359

0.74 (0.39 to 1.41)

N

*15

0.012

0.66 (0.47 to 0.92)

P

*16

0.934

0.98 (0.65 to 1.49)

N

  1. a Allele numbering according to Table S1 in Additional data file 1.
  2. b See Table S1 in Additional data file 1.
  3. CI = confidence interval; N = neutral allele; OA = osteoarthritis; OR = odds ratio; P = protective allele; RA = rheumatoid arthritis; SE = shared epitope allele.