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Table 2 99mTc accumulation values obtained at day 4 when a magnet was implanted near the left knee

From: Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice

 

mBSA + PBS

DXM suspension

Polymer microparticles

SPION suspension

Microparticles + SPIONs

Complete microparticles

 

(+)

(+)

(+)

(+)

(+)

(+)

 

1.95

0.86

1.98

1.7

2.17

1.29

 

1.7

1.33

1.35

1.75

2.08

1.65

 

1.55

1.08

1.61

1.89

2.17

1.43

 

1.83

1.38

1.64

1.54

2.15

1.18

 

2.12

1.39

1.86

1.44

2.22

1.54

Mean

1.83

1.21

1.69

1.66

2.16

1.42

SD

0.22

0.23

0.24

0.18

0.05

0.19

  1. The values are expressed as the ratio of the gamma-counting values in the treated joint (left knee) to those of the untreated joint (right knee). (+) indicates groups with a magnet. DXM, dexamethasone 21-acetate; mBSA, methyl bovine serum albumin; PBS, phosphate-buffered saline; SD, standard deviation; SPION, superparamagnetic iron oxide nanoparticle.
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Arthritis Research & Therapy

ISSN: 1478-6362

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