Table 2 Candidate biomarkers identified in array screening experiments, subsequently used for training and cross-validation in PAM

Autoantigens

   Acetyl-calpastatin(184–203)

Ace-DPMSSTYIEELGKREVTIPP- [NH]₂

[Swiss-Prot:P20810]

   Apolipoprotein E(277–296)cit

A [cit]LKSWFEPLVEDMQ [cit]QWAG

[Swiss-Prot:P02649]

   Cfc(48–65)cit2

TIHAHPGS [cit]RGG [cit]HGYHH

[Swiss-Prot:P20930]

   Clusterin(170–188)

QTHMLDVMQDHFSRASSID

[Swiss-Prot:P10909]

   Clusterin(334–353)cit2

AE [cit]LT [cit]KYNELLKSYQWKML

[Swiss-Prot:P10909]

   Fibrinogen A(616–635)cit3

THSTK [cit]GHAKS [cit]PV [cit]GIHTS

[Swiss-Prot:P02671]

   Fibromodulin(246–265)

LEQLYMEHNNVYTVPDSYFR

[Swiss-Prot:Q06828]

   H2B/e(1–20)

MPEPVKSAPVPKKGSKKAIN

[Swiss-Prot:Q16778]

   HSP60(287–297)

VLNRLKVGLQV

[Swiss-Prot:P10809]

   Osteoglycin(176–195)

NQLLKLPVLPPKLTLFNAKY

[Swiss-Prot:P20774]

   Serine protease 11(433–452)

VIISINGQSVVSANDVSDVI

[Swiss-Prot:Q92743]

   Biglycan(247–266)

EDLLRYSKLYRLGLGHNQIR

[Swiss-Prot:P21810]

   Cartilage oligomeric matrix protein(453–472)

NSAQEDSDHDGQGDACDDDD

[Swiss-Prot:P49747]

   Fibrinogen cit

n.a.

[Swiss-Prot:P02671]

Cytokines and chemokines

   Eotaxin

n.a.

[Swiss-Prot:P51671]

   Fibroblast growth factor-2

n.a.

[Swiss-Prot:P09038]

   Granulocyte- macrophage colony-stimulating factor

n.a.

[Swiss-Prot:P04141]

   IL-12p40

n.a.

[Swiss-Prot:P29460]

   IL-12p70

n.a.

[Swiss-Prot:P29459]

   IL-15

n.a.

[Swiss-Prot:P40933]

   IL-1α

n.a.

[Swiss-Prot:P01583]

   IL-1β

n.a.

[Swiss-Prot:P01584]

   IL-6

n.a.

[Swiss-Prot:P05231]

   IFNγ-inducible protein 10

n.a.

[Swiss-Prot:P02778]

   TNFα

n.a.

[Swiss-Prot:P01375]

   Monocyte chemoattractant protein-1

n.a.

[Swiss-Prot:P13500]