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Table 2 Candidate biomarkers identified in array screening experiments, subsequently used for training and cross-validation in PAM

From: Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

Variable Peptide sequence SwissProt ID
Autoantigens   
   Acetyl-calpastatin(184–203) Ace-DPMSSTYIEELGKREVTIPP- [NH]2 [Swiss-Prot:P20810]
   Apolipoprotein E(277–296)cit A [cit]LKSWFEPLVEDMQ [cit]QWAG [Swiss-Prot:P02649]
   Cfc(48–65)cit2 TIHAHPGS [cit]RGG [cit]HGYHH [Swiss-Prot:P20930]
   Clusterin(170–188) QTHMLDVMQDHFSRASSID [Swiss-Prot:P10909]
   Clusterin(334–353)cit2 AE [cit]LT [cit]KYNELLKSYQWKML [Swiss-Prot:P10909]
   Fibrinogen A(616–635)cit3 THSTK [cit]GHAKS [cit]PV [cit]GIHTS [Swiss-Prot:P02671]
   Fibromodulin(246–265) LEQLYMEHNNVYTVPDSYFR [Swiss-Prot:Q06828]
   H2B/e(1–20) MPEPVKSAPVPKKGSKKAIN [Swiss-Prot:Q16778]
   HSP60(287–297) VLNRLKVGLQV [Swiss-Prot:P10809]
   Osteoglycin(176–195) NQLLKLPVLPPKLTLFNAKY [Swiss-Prot:P20774]
   Serine protease 11(433–452) VIISINGQSVVSANDVSDVI [Swiss-Prot:Q92743]
   Biglycan(247–266) EDLLRYSKLYRLGLGHNQIR [Swiss-Prot:P21810]
   Cartilage oligomeric matrix protein(453–472) NSAQEDSDHDGQGDACDDDD [Swiss-Prot:P49747]
   Fibrinogen cit n.a. [Swiss-Prot:P02671]
Cytokines and chemokines   
   Eotaxin n.a. [Swiss-Prot:P51671]
   Fibroblast growth factor-2 n.a. [Swiss-Prot:P09038]
   Granulocyte- macrophage colony-stimulating factor n.a. [Swiss-Prot:P04141]
   IL-12p40 n.a. [Swiss-Prot:P29460]
   IL-12p70 n.a. [Swiss-Prot:P29459]
   IL-15 n.a. [Swiss-Prot:P40933]
   IL-1α n.a. [Swiss-Prot:P01583]
   IL-1β n.a. [Swiss-Prot:P01584]
   IL-6 n.a. [Swiss-Prot:P05231]
   IFNγ-inducible protein 10 n.a. [Swiss-Prot:P02778]
   TNFα n.a. [Swiss-Prot:P01375]
   Monocyte chemoattractant protein-1 n.a. [Swiss-Prot:P13500]
  1. n.a., not applicable; PAM, prediction analysis of microarrays.