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Table 1 Clinical characteristics of neurotrophins and receptors in the synovial fluids of SpA, RA, and OA patients

From: Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis

Patient Groups

 

Clinical characteristics

  

age

gender

DD (y)

SJC

TJC

CRP (mg/l)

ESR (mm)

SFc/μl

%PMN

SpA (n = 16)

median

37

6 f/10 m

5

2*

1*

10.5*

20

7025*

72

 

SD

16.8

 

5.9

1.2

1.9

23

15

8825

26

 

(range)

(16 to 65)

 

(0.3 to 18)

(1 to 4)

(0 to 8)

(1 to 99)

(3 to 54)

(2500 to 31100)

(5 to 92)

RA (n = 9)

median

49

8 f/1 m

5

5#

3#

11.7#

26

7950#

76

 

SD

15.3

 

9.2

3.2

1.8

29

8.8

3645

11

 

(range)

(37 to 77)

 

(1 to 26)

(2 to 13)

(2 to 7)

(7.5 to -95)

(12 to 67)

(2600 to 1300)

(50 to 90)

OA (n = 7)

median

67

5 f/2 m

6

1

1

3

17

700

60

 

SD

5.8

 

5.7

0.5

0.4

1.1

5.6

1096

33

 

(range)

(58 to 75)

 

(2 to 18)

(1 to 2)

(1 to 2)

(1.6 to 4.5)

(12 to 25)

(100 to 3250)

(5 to 90)

  1. Table 1 shows the clinical data and parameters of disease activity of 16 spondyloarthritis (SpA), 9 rheumatoid arthritis (RA), and 7 osteoarthritis (OA) patients used for the RT-PCR measurements on the synovial fluid samples. Swollen joint count (SJC), tender joint count (TJC), C-reactive protein (CRP), and synovial fluid (SF) leukocyte counts were higher in both SpA (*) and RA (#) as compared with OA; Mann Whitney U test; P < 0.05).
  2. DD = disease duration given in years; ESR = erythrocyte sedimentation rate; f = female; m = male; PMN = percentage of polymorphonuclear cells of SF leukocytes; OA = osteoarthritis; RA = rheumatoid arthritis; SD = standard deviation; SpA = spondyloarthritis.