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Table 1 Clinical characteristics of neurotrophins and receptors in the synovial fluids of SpA, RA, and OA patients

From: Nerve growth factor and receptor expression in rheumatoid arthritis and spondyloarthritis

Patient Groups   Clinical characteristics
   age gender DD (y) SJC TJC CRP (mg/l) ESR (mm) SFc/μl %PMN
SpA (n = 16) median 37 6 f/10 m 5 2* 1* 10.5* 20 7025* 72
  SD 16.8   5.9 1.2 1.9 23 15 8825 26
  (range) (16 to 65)   (0.3 to 18) (1 to 4) (0 to 8) (1 to 99) (3 to 54) (2500 to 31100) (5 to 92)
RA (n = 9) median 49 8 f/1 m 5 5# 3# 11.7# 26 7950# 76
  SD 15.3   9.2 3.2 1.8 29 8.8 3645 11
  (range) (37 to 77)   (1 to 26) (2 to 13) (2 to 7) (7.5 to -95) (12 to 67) (2600 to 1300) (50 to 90)
OA (n = 7) median 67 5 f/2 m 6 1 1 3 17 700 60
  SD 5.8   5.7 0.5 0.4 1.1 5.6 1096 33
  (range) (58 to 75)   (2 to 18) (1 to 2) (1 to 2) (1.6 to 4.5) (12 to 25) (100 to 3250) (5 to 90)
  1. Table 1 shows the clinical data and parameters of disease activity of 16 spondyloarthritis (SpA), 9 rheumatoid arthritis (RA), and 7 osteoarthritis (OA) patients used for the RT-PCR measurements on the synovial fluid samples. Swollen joint count (SJC), tender joint count (TJC), C-reactive protein (CRP), and synovial fluid (SF) leukocyte counts were higher in both SpA (*) and RA (#) as compared with OA; Mann Whitney U test; P < 0.05).
  2. DD = disease duration given in years; ESR = erythrocyte sedimentation rate; f = female; m = male; PMN = percentage of polymorphonuclear cells of SF leukocytes; OA = osteoarthritis; RA = rheumatoid arthritis; SD = standard deviation; SpA = spondyloarthritis.