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Table 1 Clinical and demographic characteristics of the RA patients

From: Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

     Treatment trial
  Healthy controls Long-standing RA RA patients for synovium collection MTX only Infliximab and MTX
Number of subjects 40 33 10 8 15
Age (years) 44 ± 9 57 ± 12 62 ± 10 52 ± 16 45 ± 11
Female/male ratio 26:14 28:5 9:1 7:1 13:2
Disease duration (years) -- 13 ± 12 13.5 ± 11.0 5.7 ± 1.5 3.0 ± 0.5
% RF positive patients -- 79% 90% 50% 73%
ESR (mm/hour) -- 36 ± 27 -- 36.9 ± 14.3 60.2 ± 30.3
CRP (mg/dl) -- <0.4 ± 9.75 2.8 ± 2.3 0.8 ± 1.1 1.8 ± 1.9
% Patients on MTX (dose) -- 85% (15 mg/wk) 60% (4 mg/wk) 100% (14 mg/wk) 100% (14 mg/wk)
% Patients on GC (dose) -- 49% (5 mg/day) 80% (5 mg/day) 50% (6 mg/day) 64% (6 mg/day)
% Patients on other DMARD -- 82% 50% -- --
  1. Data are means ± standard deviation.
  2. CRP = C-reactive protein; DMARD = disease-modifying anti-rheumatic drug; ESR = erythrocyte sedimentation rate; GC = glucocorticoids; MTX = methotrexate; RA = rheumatoid arthritis; RF = rheumatoid factor.