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Table 3 Chemokine receptor expression by CD19+ CD27+ memory B cells from peripheral blood of healthy donors and RA patients and in RA synovium

From: Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

  Peripheral blood Synovium
Chemokine receptor Control (n = 13) RA (n = 20) (n = 10)
CXCR1 5.0 ± 0.6% 16.9 ± 1.2%a 39.0 ± 2.2%b
CXCR2 3.4 ± 0.4% 7.7 ± 0.6%a 31.2 ± 1.6%b
CXCR4 60.0 ± 0.9% 47.5 ± 2.3%a 92.1 ± 0.7%b
CCR2 2.8 ± 0.4% 7.6 ± 0.6%a 28.7 ± 1.8%b
  1. a indicates significant difference (P < 0.02) between controls and patients with rheumatoid arthritis (RA);
  2. b indicates significant difference (P < 0.00001) between RA blood and synovium.
  3. Data are means ± standard error of the mean.