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Table 3 Chemokine receptor expression by CD19+ CD27+ memory B cells from peripheral blood of healthy donors and RA patients and in RA synovium

From: Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

 

Peripheral blood

Synovium

Chemokine receptor

Control (n = 13)

RA (n = 20)

(n = 10)

CXCR1

5.0 ± 0.6%

16.9 ± 1.2%a

39.0 ± 2.2%b

CXCR2

3.4 ± 0.4%

7.7 ± 0.6%a

31.2 ± 1.6%b

CXCR4

60.0 ± 0.9%

47.5 ± 2.3%a

92.1 ± 0.7%b

CCR2

2.8 ± 0.4%

7.6 ± 0.6%a

28.7 ± 1.8%b

  1. a indicates significant difference (P < 0.02) between controls and patients with rheumatoid arthritis (RA);
  2. b indicates significant difference (P < 0.00001) between RA blood and synovium.
  3. Data are means ± standard error of the mean.