Figure 2

Treating spontaneous arthritis with a TLR4 antagonist suppresses the clinical and histological characteristics of arthritis. Abdollahi-Roodsaz and colleagues have recently shown that treating collagen-induced arthritis (left-hand side) with a TLR4 antagonist suppresses the clinical and histological characteristics of arthritis (right-hand side). Histological images of knee joints are shown, stained with hematoxylin and eosin. Arrow indicates inflammatory cell influx and chondrocyte cell death. Image taken from [21]. Reproduced with permission of John Wiley and Sons.