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Table 3 Fold change and threshold cycle for aspartate proteases showing significant difference between OA and NOF

From: Degradome expression profiling in human articular cartilage

Gene name Gene symbol P value Fold change OA/NOF Median threshold cycle
β-Secretase 1 BACE1 0.00005 2.9 30.7
Nuclear receptor interacting protein 2 NRIP2 0.00014 3.7 33.8
Presenilin homolog 4/SPPL2B SPPL2B 0.00028 1.9 28.1
Cathepsin D CTSD 0.00071 3.4 24.5
Presenilin 2 PSEN2 0.00137 1.9 30.1
Nuclear receptor interacting protein 3 NRIP3 0.00170 3.7 34.6
Pepsin A PGA3/4/5 0.00170 6.8 35.3
  1. Fold change and median threshold cycle for all aspartate protease genes showing significant difference at P < 0.01 between osteoarthritis (OA) versus fracture to the neck of femur (NOF). P value from the Mann-Whitney U test.